Whenever we pray with the Saints and the Most Holy Theotokos, then we are no longer alone. The Saints are alive in Christ. Truly, then, we never pray alone as we are surrounded by so great a witness of angels, saints, and the Most Holy Theotokos.
This, then, is one of my favorite prayers. It makes my fears vanish, and most importantly, I no longer feel alone, as I feel the presence of Our Lord, His Mother the Theotokos, and all the angels and saints. It is truly glorious and a taste of what Heaven will be like.
O Lord Jesus Christ, through the prayers of Thy Most Pure Theotokos and all Thy Saints, have mercy on us and save us.